The amnion is a membrane of the uterine placenta that envelopes a fetus and retains amniotic fluid; once labor is completed, however, it is routinely discarded.

A thick basal lamina made of collagen (type III, IV, V), laminin and nidgen is present in the amnion which, together with the lack of blood vessel components, makes the amnion unique as compared with other tissues. These characteristics make rejection reactions unlikely.

ArBlast has developed a novel manufacturing technology to remove epithelial cells covering the amnion, without sacrificing the above mentioned innate characteristics of the amnion, resulting in purified collagen sheet material free from pathogenicity and antigenicity. Such sheet is suitable as a culture medium for various cells, and can be used to prevent postoperative adhesions in the surgical field.